Lens regeneration in adult mice is possible when the lens capsule is left behind after
lentectomy. The lens is regenerated by the remaining adherent lens epithelial cells, which
differentiate to form lens fibres within days, showing normal morphology and bow regions.
Epithelial to mesenchymal cell transformation is also seen during the early stages. The
mouse, therefore, can become an indispensable animal model for cataract research, surgery
and therapy.