Treg cells, life history, and diversity

C Benoist, D Mathis - Cold Spring Harbor perspectives …, 2012 - cshperspectives.cshlp.org
C Benoist, D Mathis
Cold Spring Harbor perspectives in biology, 2012cshperspectives.cshlp.org
Regulatory T cells expressing the FoxP3 transcription factor have a profound and
nonredundant role in several aspects of immunological tolerance. We will review here the
specification of this lineage, its population dynamics, and the diversity of subphenotypes that
correlate with their diverse roles in controlling inflammation in a variety of settings.
Regulatory T cells expressing the FoxP3 transcription factor have a profound and nonredundant role in several aspects of immunological tolerance. We will review here the specification of this lineage, its population dynamics, and the diversity of subphenotypes that correlate with their diverse roles in controlling inflammation in a variety of settings.
cshperspectives.cshlp.org