Serum YKL-40 is increased in patients with hepatic fibrosis
JS Johansen, P Christoffersen, S Møller, PA Price… - Journal of …, 2000 - Elsevier
Background/Aims: YKL-40, a mammalian member of the chitinase family, is a lectin that
binds heparin and chitin. The function of YKL-40 is unknown, but it may function in tissue
remodelling. The aims of this study were to assess the level of circulating YKL-40 in patients
with various kinds and degree of chronic liver disease and its possible relation to liver
fibrosis. Methods: Serum YKL-40 levels were determined byradioimmunoassay in 129
patients with suspected liver disease and related to histological findings and …
binds heparin and chitin. The function of YKL-40 is unknown, but it may function in tissue
remodelling. The aims of this study were to assess the level of circulating YKL-40 in patients
with various kinds and degree of chronic liver disease and its possible relation to liver
fibrosis. Methods: Serum YKL-40 levels were determined byradioimmunoassay in 129
patients with suspected liver disease and related to histological findings and …