[HTML][HTML] Multi-drug-resistant Staphylococcus aureus and future chemotherapy

K Hiramatsu, Y Katayama, M Matsuo, T Sasaki… - Journal of Infection and …, 2014 - Elsevier
Staphylococcus (S.) aureus silently stays as our natural flora, and yet sometimes threatens
our life as a tenacious pathogen. In addition to its ability to outwit our immune system, its
multi-drug resistance phenotype makes it one of the most intractable pathogenic bacteria in
the history of antibiotic chemotherapy. It conquered practically all the antibiotics that have
been developed since 1940s. In 1961, the first MRSA was found among S. aureus clinical
isolates. Then MRSA prevailed throughout the world as a multi-resistant hospital pathogen …