[HTML][HTML] First-in-human, first-in-class phase I trial of the anti-CD47 antibody Hu5F9-G4 in patients with advanced cancers

BI Sikic, N Lakhani, A Patnaik, SA Shah… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
BI Sikic, N Lakhani, A Patnaik, SA Shah, SR Chandana, D Rasco, AD Colevas, T O'Rourke…
Journal of Clinical Oncology, 2019ncbi.nlm.nih.gov
First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients
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Abstract
PURPOSE
To evaluate the safety, pharmacokinetics, and pharmacodynamics of Hu5F9-G4 (5F9), a humanized IgG4 antibody that targets CD47 to enable phagocytosis.
ncbi.nlm.nih.gov