Reversal of TGFβ1-driven profibrotic state in patients with pulmonary fibrosis

HA Chapman, Y Wei, G Montas, D Leong… - … England Journal of …, 2020 - Mass Medical Soc
HA Chapman, Y Wei, G Montas, D Leong, JA Golden, BN Trinh, PJ Wolters, CJ Le Saux
New England Journal of Medicine, 2020Mass Medical Soc
EGCG and Pulmonary Fibrosis Nine patients who were scheduled to undergo lung biopsy
for pulmonary fibrosis were given epigallocatechin gallate (EGCG) for 2 weeks. Levels of
fibrotic markers in lung-biopsy samples were lower in the EGCG-treated patients than in 10
similar, but untreated, patients.
EGCG and Pulmonary Fibrosis
Nine patients who were scheduled to undergo lung biopsy for pulmonary fibrosis were given epigallocatechin gallate (EGCG) for 2 weeks. Levels of fibrotic markers in lung-biopsy samples were lower in the EGCG-treated patients than in 10 similar, but untreated, patients.
The New England Journal Of Medicine