Periodontitis is a polymicrobial disease caused by complex interactions between distinct
pathogens in a biofilm resulting in the destruction of periodontal tissues. It seems evident
that unknown microorganisms might be involved in onset or progression of periodontitis. For
many decades, research in the field of oral microbiology failed to identify certain subgingival
microbiota due to technical limitations but, over a period of 12 years using molecular
approaches and sequencing techniques, it became feasible to reveal the existence of new …