Proteins of the Myc network: essential regulators of cell growth and differentiation
M Henriksson, B Lüscher - Advances in cancer research, 1996 - Elsevier
Publisher Summary This chapter focuses on the proteins of the Myc network that are
essential regulators of cell growth and differentiation. The identification of the Myc partner,
Max, in 1991 and the subsequent realization that this protein is the essential dimeric partner
for all known c-Myc functions was a major boost to the field and led to a number of very
interesting observations and findings. The chapter focuses on c-Myc's role as a transcription
factor in the regulation of cell growth, apoptosis, and transformation. The most exciting …
essential regulators of cell growth and differentiation. The identification of the Myc partner,
Max, in 1991 and the subsequent realization that this protein is the essential dimeric partner
for all known c-Myc functions was a major boost to the field and led to a number of very
interesting observations and findings. The chapter focuses on c-Myc's role as a transcription
factor in the regulation of cell growth, apoptosis, and transformation. The most exciting …
