Background Although immune responses directed against antigens from the intestinal
microbiota are observed in certain diseases, the normal human adaptive immune response
to intestinal microbiota is poorly defined. Objective Our goal was to assess the adaptive
immune response to the intestinal microbiota present in 143 healthy adults and compare this
response with the response observed in 52 children and their mothers at risk of having
allergic disease. Methods Human serum was collected from adults and children followed …