MicroRNA-29 family, a crucial therapeutic target for fibrosis diseases
Y He, C Huang, X Lin, J Li - Biochimie, 2013 - Elsevier
MicroRNAs (miRNAs) are a class of approximately 20-nucleotides single-stranded
endogenous RNAs that regulate gene expression at the post-transcriptional level. miRNAs
have recently been known to regulate cell proliferation, differentiation, and apoptosis.
Fibrosis is the leading cause of organ dysfunction in diseases and results from an imbalance
in the turnover of extracellular matrix components. Accumulating studies have demonstrated
that miR-29 family participates in the development of liver fibrosis, renal fibrosis, pulmonary …
endogenous RNAs that regulate gene expression at the post-transcriptional level. miRNAs
have recently been known to regulate cell proliferation, differentiation, and apoptosis.
Fibrosis is the leading cause of organ dysfunction in diseases and results from an imbalance
in the turnover of extracellular matrix components. Accumulating studies have demonstrated
that miR-29 family participates in the development of liver fibrosis, renal fibrosis, pulmonary …