The pathogenesis and treatment of theCytokine Storm'in COVID-19
Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory
control of proinflammatory cytokine production, both at local and systemic levels. The
disease progresses rapidly, and the mortality is high. Some evidence shows that, during the
coronavirus disease 2019 (COVID-19) epidemic, severe deterioration in some patients has
been closely associated with dysregulated and excessive cytokine release. This article …
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory
control of proinflammatory cytokine production, both at local and systemic levels. The
disease progresses rapidly, and the mortality is high. Some evidence shows that, during the
coronavirus disease 2019 (COVID-19) epidemic, severe deterioration in some patients has
been closely associated with dysregulated and excessive cytokine release. This article …