Quantitation of tremor in response to β-adrenergic receptor stimulation in primates: relationship with hypokalemia
B Tesfamariam, T Waldron, AA Seymour - Journal of pharmacological and …, 1998 - Elsevier
The primary adverse effect of stimulation of β2-adrenergic receptors is elicitation of tremor.
Tremor measurements in response to β2-adrenergic receptor stimulation were performed in
a quantitative manner using a modified miniature semiconductor accelerometer in African
green monkeys. The accelerometer was taped to the middle finger tip of anesthetized
monkeys, and recordings of onset, duration and peak tremor responses were obtained. The
selective β2-adrenergic agonist, salbutamol (0.5 mg/kg iv), caused a marked increase in …
Tremor measurements in response to β2-adrenergic receptor stimulation were performed in
a quantitative manner using a modified miniature semiconductor accelerometer in African
green monkeys. The accelerometer was taped to the middle finger tip of anesthetized
monkeys, and recordings of onset, duration and peak tremor responses were obtained. The
selective β2-adrenergic agonist, salbutamol (0.5 mg/kg iv), caused a marked increase in …