Dynamic changes in maternal decidual leukocyte populations from first to second trimester gestation
M Kwan, A Hazan, J Zhang, RL Jones, LK Harris… - Placenta, 2014 - Elsevier
Introduction Decidual leukocytes are critical to the development of the fetomaternal interface,
regulating tolerance to the semi-allogeneic fetus and vascular transformation of the uterine
spiral arteries. Despite the continuation of these processes beyond the first trimester of
pregnancy, the second trimester has largely been unstudied, with investigation focusing on
early gestation and term tissues. We sought to characterize changes in decidual leukocyte
populations from first to second trimester. Methods Multicolor flow cytometry was performed …
regulating tolerance to the semi-allogeneic fetus and vascular transformation of the uterine
spiral arteries. Despite the continuation of these processes beyond the first trimester of
pregnancy, the second trimester has largely been unstudied, with investigation focusing on
early gestation and term tissues. We sought to characterize changes in decidual leukocyte
populations from first to second trimester. Methods Multicolor flow cytometry was performed …
