Micronucleus frequencies in urothelial cells of catheterized patients with chronic bladder inflammation
LJ Hofseth, BP Dunn, MP Rosin - Mutation Research/Fundamental and …, 1996 - Elsevier
Epidemiological studies suggest an association between chronic inflammation and
increased risk for cancer, although the mechanism underlying this relationship is
unresolved. In the present study, we test the hypothesis that DNA damage is induced in the
epithelium of tissues during such inflammation by products of activated inflammatory cells.
Individuals on long-term indwelling urinary catheterization were used as a study population.
These individuals have chronic bladder inflammation and, as a population, an increased risk …
increased risk for cancer, although the mechanism underlying this relationship is
unresolved. In the present study, we test the hypothesis that DNA damage is induced in the
epithelium of tissues during such inflammation by products of activated inflammatory cells.
Individuals on long-term indwelling urinary catheterization were used as a study population.
These individuals have chronic bladder inflammation and, as a population, an increased risk …