Comparative genomic hybridization analysis of human parathyroid tumors
SK Agarwal, E Schröck, MB Kester, AL Burns… - Cancer Genetics and …, 1998 - Elsevier
Primary hyperparathyroidism is characterized by hypercalcemia and elevated parathyroid
hormone levels. It can be caused by overactivity of one (adenoma or carcinoma) or more
(hyperplasia or multiple adenoma) parathyroid glands. Parathyroid adenoma and
hyperplasia are usually mono-or oligoclonal neoplasms. To establish whether parathyroid
cancer has a genetic composition distinct from parathyroid adenoma, we analyzed 10
adenoma and 10 carcinoma cases by comparative genomic hybridization (CGH). Results …
hormone levels. It can be caused by overactivity of one (adenoma or carcinoma) or more
(hyperplasia or multiple adenoma) parathyroid glands. Parathyroid adenoma and
hyperplasia are usually mono-or oligoclonal neoplasms. To establish whether parathyroid
cancer has a genetic composition distinct from parathyroid adenoma, we analyzed 10
adenoma and 10 carcinoma cases by comparative genomic hybridization (CGH). Results …