[PDF][PDF] Apparent normal phenotype of Fgf6-/-mice.

F Fiore, J Planche, P Gibier, A Sebille… - International Journal …, 2004 - scholar.archive.org
F Fiore, J Planche, P Gibier, A Sebille, O Delapeyriere, D Birnbaum
International Journal of Developmental Biology, 2004scholar.archive.org
To study the role o! the sixth member ofthe FGF (fibroblast growth factor) family whose
expression is restricted to skeletal muscle. we have derived mouse mutants with a
homozygous disruption of the Fgf6gene. The animals are viable, fertile and apparently
normal, indicating that FGF6 is not required for vital functions in the laboratory mouse.
Abstract
To study the role o! the sixth member ofthe FGF (fibroblast growth factor) family whose expression is restricted to skeletal muscle. we have derived mouse mutants with a homozygous disruption of the Fgf6gene. The animals are viable, fertile and apparently normal, indicating that FGF6 is not required for vital functions in the laboratory mouse.
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