[HTML][HTML] The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
MS Brown, JL Goldstein - Cell, 1997 - cell.com
MS Brown, JL Goldstein
Cell, 1997•cell.comAnimal cells must regulate their biosynthetic pathways so as to produce the required
amounts of end-products without risking overproduction. Such control is particularly
important in cholesterol homeostasis because cholesterol must be supplied for many
cellular functions, including two recently recognized ones: formation of caveolae (
amounts of end-products without risking overproduction. Such control is particularly
important in cholesterol homeostasis because cholesterol must be supplied for many
cellular functions, including two recently recognized ones: formation of caveolae (
Animal cells must regulate their biosynthetic pathways so as to produce the required amounts of end-products without risking overproduction. Such control is particularly important in cholesterol homeostasis because cholesterol must be supplied for many cellular functions, including two recently recognized ones: formation of caveolae (
cell.com