Anti-dsDNA, anti-Sm antibodies, and the lupus anticoagulant: significant factors associated with lupus nephritis
Background: Lupus nephritis (LN) is a common manifestation in patients with systemic lupus
erythematosus (SLE). Autoantibodies and ethnicity have been associated with LN, but the
results are controversial. Objective: To study the immunological and demographic factors
associated with the development of LN. Patients and methods: A retrospective case-control
study of 127 patients with biopsy-proven LN, and 206 randomly selected patients with SLE
without nephritis as controls was designed. All patients had attended our lupus unit during …
erythematosus (SLE). Autoantibodies and ethnicity have been associated with LN, but the
results are controversial. Objective: To study the immunological and demographic factors
associated with the development of LN. Patients and methods: A retrospective case-control
study of 127 patients with biopsy-proven LN, and 206 randomly selected patients with SLE
without nephritis as controls was designed. All patients had attended our lupus unit during …
