Surgery and anaesthesia result in a variety of metabolic and endocrine responses, which
result in a generalised state of immunosuppression in the immediate post-operative period.
Surgery induced immunosuppression has been implicated in the development of post-
operative septic complications and tumour metastasis formation. In addition the
effectiveness of many treatments in the adjuvant setting is dependent on a functioning
immune system. By understanding the mechanisms contributing to surgery-induced …