MicroRNAs in cardiovascular biology and heart disease

D Catalucci, P Gallo, G Condorelli - Circulation: Cardiovascular …, 2009 - Am Heart Assoc
D Catalucci, P Gallo, G Condorelli
Circulation: Cardiovascular Genetics, 2009Am Heart Assoc
MicroRNAs play important roles in many cellular and biological functions via the regulation
of mRNA target translation. In the cardiovascular field, microRNAs are now acknowledged
as fundamental in regulating the expression of genes that governs physiological and
pathological myocardial adaptation to stress. Here, we review recent progress in the
understanding of microRNA functions and their involvement in heart disease.
MicroRNAs play important roles in many cellular and biological functions via the regulation of mRNA target translation. In the cardiovascular field, microRNAs are now acknowledged as fundamental in regulating the expression of genes that governs physiological and pathological myocardial adaptation to stress. Here, we review recent progress in the understanding of microRNA functions and their involvement in heart disease.
Am Heart Assoc