High-throughput non-heme iron assay for animal tissues
MA Grundy, N Gorman, PR Sinclair, MJ Chorney… - Journal of biochemical …, 2004 - Elsevier
Iron has been widely studied in nearly every realm of biology. However, current
methodologies, such as genetic mapping or mutation screening, have been difficult to apply
due to the lack of robust high-throughput methods for quantifying iron levels from cells or
tissues. The measurement of total iron levels in tissues, usually done with atomic absorption
spectroscopy, is impractical for large numbers of samples and includes the contribution of
heme iron from hemoglobin contained in red blood cells. The measurement of non-heme …
methodologies, such as genetic mapping or mutation screening, have been difficult to apply
due to the lack of robust high-throughput methods for quantifying iron levels from cells or
tissues. The measurement of total iron levels in tissues, usually done with atomic absorption
spectroscopy, is impractical for large numbers of samples and includes the contribution of
heme iron from hemoglobin contained in red blood cells. The measurement of non-heme …
