The genetic determinants of renal allograft rejection

M Hernandez-Fuentes, CP Stapleton… - American Journal of …, 2018 - amjtransplant.org
The 2 recipient genetic loci highlighted in their paper, 3 rs10765602 (gene annotation
CCDC67) and rs7976329 (gene annotation PTPRO), were well imputed in our study (INFO>
0.95) and neither reached genome-wide significance in our reported analyses. 2 To provide
additional confidence, we have reanalyzed our data following reimputation to the 1000
Genomes phase 3 reference panel via the Sanger Imputation Service (www. imputation.
sanger. ac. uk) using Eagle and the Positional Burrows-Wheeler Transform package. 4 …