[HTML][HTML] Discoveries of the phosphatidate phosphatase genes in yeast published in the Journal of Biological Chemistry

GM Carman - Journal of Biological Chemistry, 2019 - ASBMB
This JBC Review on the discoveries of yeast phosphatidate (PA) phosphatase genes is
dedicated to Dr. Herbert Tabor, Editor-in-Chief of the Journal of Biological Chemistry (JBC)
for 40 years, on the occasion of his 100th birthday. Here, I reflect on the discoveries of the
APP1, DPP1, LPP1, and PAH1 genes encoding all the PA phosphatase enzymes in yeast.
PA phosphatase catalyzes PA dephosphorylation to generate diacylglycerol; both substrate
and product are key intermediates in the synthesis of membrane phospholipids and …