Environmental neurotoxic exposure to agrochemicals has been implicated in the
etiopathogenesis of Parkinson's disease (PD). The widely used herbicide paraquat is
among the few environmental chemicals potentially linked with PD. Since epigenetic
changes are beginning to emerge as key mechanisms in neurodegenerative diseases,
herein we examined the effects of paraquat on histone acetylation, a major epigenetic
change in chromatin that can regulate gene expression, chromatin remodeling, cell survival …