[HTML][HTML] Endothelial injury and glycocalyx degradation in critically ill coronavirus disease 2019 patients: implications for microvascular platelet aggregation
Objectives: Coronavirus disease 2019 is caused by the novel severe acute respiratory
syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular
thrombosis, which may contribute to mortality. Our aim was to profile plasma thrombotic
factors and endothelial injury markers in critically ill coronavirus disease 2019 ICU patients
to help understand their thrombotic mechanisms. Design: Daily blood coagulation and
thrombotic factor profiling with immunoassays and in vitro experiments on human pulmonary …
syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular
thrombosis, which may contribute to mortality. Our aim was to profile plasma thrombotic
factors and endothelial injury markers in critically ill coronavirus disease 2019 ICU patients
to help understand their thrombotic mechanisms. Design: Daily blood coagulation and
thrombotic factor profiling with immunoassays and in vitro experiments on human pulmonary …