Nonalcoholic fatty liver disease, insulin resistance, and ceramides
VT Samuel, GI Shulman - New England Journal of Medicine, 2019 - Mass Medical Soc
New England Journal of Medicine, 2019•Mass Medical Soc
Mediators of Insulin Resistance Insulin resistance is a precursor to and accelerant of
coexisting conditions such as type 2 diabetes, atherosclerosis, and nonalcoholic liver
disease. A recent study of mouse models implicates elevated levels of ceramide and their
effect on mitochondrial function in the mediation of cellular insulin resistance.
coexisting conditions such as type 2 diabetes, atherosclerosis, and nonalcoholic liver
disease. A recent study of mouse models implicates elevated levels of ceramide and their
effect on mitochondrial function in the mediation of cellular insulin resistance.
Mediators of Insulin Resistance
Insulin resistance is a precursor to and accelerant of coexisting conditions such as type 2 diabetes, atherosclerosis, and nonalcoholic liver disease. A recent study of mouse models implicates elevated levels of ceramide and their effect on mitochondrial function in the mediation of cellular insulin resistance.
The New England Journal Of Medicine