Although counterregulatory hormones and mediators of the fight-or-flight responses are well
defined at many levels, how energy stores per se are integrated into this system remains an
enigmatic question. Recent years have seen the adipose tissue become a central focus for
mediating intracellular signaling and communication through the release of a variety of
bioactive lipids and substrates, as well as various adipokines. A critical integration node
among these mediators and responses is controlled by FA binding protein 4 (FABP4), also …