Cervicovaginal microbial communities deficient in Lactobacillus species are associated with second trimester short cervix

KD Gerson, C McCarthy, MA Elovitz, J Ravel… - American journal of …, 2020 - Elsevier
Background The cervix functions as a barrier to ascending pathogens in pregnancy. Short
cervical length and lack of cervicovaginal Lactobacillus species are risk factors for
spontaneous preterm birth; however, whether they interact to increase risk remains
unknown. Objective We sought to examine the relationship between cervicovaginal
microbiota and short cervix as well as their combined impact on spontaneous preterm birth
risk. Study Design This was a secondary analysis of a prospective nested, case-control …