[HTML][HTML] Unraveling V (D) J recombination: insights into gene regulation
D Jung, FW Alt - Cell, 2004 - cell.com
D Jung, FW Alt
Cell, 2004•cell.comAbstract V (D) J recombination assembles antigen receptor genes from component gene
segments. We review findings that have shaped our current understanding of this
remarkable mechanism, with a focus on two major reports—the first detailed comparison of
germline and rearranged antigen receptor loci and the discovery of the recombination
activating gene-1.
segments. We review findings that have shaped our current understanding of this
remarkable mechanism, with a focus on two major reports—the first detailed comparison of
germline and rearranged antigen receptor loci and the discovery of the recombination
activating gene-1.
Abstract
V(D)J recombination assembles antigen receptor genes from component gene segments. We review findings that have shaped our current understanding of this remarkable mechanism, with a focus on two major reports—the first detailed comparison of germline and rearranged antigen receptor loci and the discovery of the recombination activating gene-1.
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