[HTML][HTML] Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration

N Arraud, R Linares, S Tan, C Gounou… - Journal of Thrombosis …, 2014 - Elsevier
Background Plasma and other body fluids contain membranous extracellular vesicles (EVs),
which are considered to derive from activated or apoptotic cells. EVs participate in
physiological and pathological processes and have potential applications in diagnostics or
therapeutics. Knowledge on EVs is, however, limited, mainly due to their sub‐micrometer
size and to intrinsic limitations in methods applied for their characterization. Objectives Our
aim was to provide a comprehensive description of EVs from plasma of healthy subjects …