[HTML][HTML] Beneficial effect of microinjected trehalose on the cryosurvival of human oocytes

A Eroglu, M Toner, TL Toth - Fertility and sterility, 2002 - Elsevier
Objective: To determine the effectiveness of trehalose as an intracellular cryoprotectant for
the cryopreservation of human oocytes. Design: In vitro comparative study. Setting: Clinical
and academic research environment at a medical school teaching hospital. Patient (s):
Women undergoing in vitro fertilization (IVF). Intervention (s): Discarded human oocytes,
obtained from IVF patients, were randomly distributed into three groups: control group (no
trehalose), extracellular trehalose group (0.5 M extracellular trehalose), and intracellular …