[HTML][HTML] Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high d-glucose conditions
Abstract Diabetes mellitus type 2 (DMT2) is characterized by hyperglycemia and associated
with low grade inflammation affecting both endothelial cells and monocytes. Exosomes are
nanovesicles, allow communication between endothelial cells and monocytes and have
been associated with diabetic complications. In this study we evaluated whether high
glucose can activate monocytes and endothelial cells and whether exosomes play a role in
this activation. Moreover, we studied whether endothelial cells and monocytes communicate …
with low grade inflammation affecting both endothelial cells and monocytes. Exosomes are
nanovesicles, allow communication between endothelial cells and monocytes and have
been associated with diabetic complications. In this study we evaluated whether high
glucose can activate monocytes and endothelial cells and whether exosomes play a role in
this activation. Moreover, we studied whether endothelial cells and monocytes communicate …