[HTML][HTML] Oxidative stress and nuclear factor κB (NF-κB) increase peritoneal filtration and contribute to ascites formation in nephrotic syndrome
K Udwan, G Brideau, M Fila, A Edwards, B Vogt… - Journal of Biological …, 2016 - ASBMB
Water accumulation in the interstitium (edema) and the peritoneum (ascites) of nephrotic
patients is classically thought to stem from the prevailing low plasma albumin concentration
and the decreased transcapillary oncotic pressure gradient. However, several clinical and
experimental observations suggest that it might also stem from changes in capillary
permeability. We addressed this hypothesis by studying the peritoneum permeability of rats
with puromycin aminonucleoside-induced nephrotic syndrome. The peritoneum of …
patients is classically thought to stem from the prevailing low plasma albumin concentration
and the decreased transcapillary oncotic pressure gradient. However, several clinical and
experimental observations suggest that it might also stem from changes in capillary
permeability. We addressed this hypothesis by studying the peritoneum permeability of rats
with puromycin aminonucleoside-induced nephrotic syndrome. The peritoneum of …
