[HTML][HTML] Identification of a general transcription factor TFIIAα/β homolog selectively expressed in testis

AB Upadhyaya, SH Lee, J DeJong - Journal of Biological Chemistry, 1999 - ASBMB
In this paper we describe the isolation of a cDNA that encodes a human TFIIAα/β-likefactor
(ALF). The open reading frame of ALF predicts a protein of 478 amino acids that contains
characteristic N-and C-terminal conserved domains separated by an internal nonconserved
domain. In addition, a rare ALF-containing cDNA, which possesses an extended N terminus
(Stoned B/TFIIAα/β-like factor; SALF) has also been identified. The results of Northern and
dot blot analyses show that ALF is expressed almost exclusively in testis; in contrast …