The players: cells involved in glomerular disease

AR Kitching, HL Hutton - Clinical Journal of the American Society …, 2016 - journals.lww.com
Glomerular diseases are common and important. They can arise from systemic inflammatory
or metabolic diseases that affect the kidney. Alternately, they are caused primarily by local
glomerular abnormalities, including genetic diseases. Both intrinsic glomerular cells and
leukocytes are critical to the healthy glomerulus and to glomerular dysregulation in disease.
Mesangial cells, endothelial cells, podocytes, and parietal epithelial cells within the
glomerulus all play unique and specialized roles. Although a specific disease often primarily …