Leukotrienes and lipoxins—new potential performers in the regulation of human myelopoiesis
L Stenke, P Reizenstein, JÅ Lindgren - Leukemia research, 1994 - Elsevier
Leukotrienes and lipoxins are bioactive lipoxygenase products formed by leukocytes alone
or in collaboration with other cells. While the physiological role of lipoxins remains to be
clarified, accumulating evidence shows that leukotrienes are important mediators in asthma
and inflammation. Consequently, recent clinical trials with leukotriene D 4 receptor
antagonists and 5-lipoxygenase inhibitors have demonstrated marked reduction of airway
symptoms in asthmatic patients. In addition, both leukotrienes and lipoxins have been …
or in collaboration with other cells. While the physiological role of lipoxins remains to be
clarified, accumulating evidence shows that leukotrienes are important mediators in asthma
and inflammation. Consequently, recent clinical trials with leukotriene D 4 receptor
antagonists and 5-lipoxygenase inhibitors have demonstrated marked reduction of airway
symptoms in asthmatic patients. In addition, both leukotrienes and lipoxins have been …