[HTML][HTML] Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of …

RE Abdulnour, HP Sham, DN Douda, RA Colas… - Mucosal …, 2016 - Elsevier
Bacterial pneumonia is a leading cause of morbidity and mortality worldwide. Host
responses to contain infection and mitigate pathogen-mediated lung inflammation are
critical for pneumonia resolution. Aspirin-triggered resolvin D1 (AT-RvD1; 7S, 8R, 17R-
trihydroxy-4Z, 9E, 11E, 13Z, 15E, 19Z-docosahexaenoic acid) is a lipid mediator (LM) that
displays organ-protective actions in sterile lung inflammation, and regulates pathogen-
initiated cellular responses. Here, in a self-resolving murine model of Escherichia coli …