BACKGROUND: Grass pollen immunotherapy for allergic rhinitis is a disease-modifying
treatment that results in long-term clinical tolerance lasting years after treatment
discontinuation. Active treatment is associated with generation of inhibitory grass pollen–
specific IgG antibodies capable of blocking allergen-IgE interactions. OBJECTIVES: We
sought to investigate the involvement of IgG-associated inhibitory antibodies with long-term
clinical tolerance after discontinuation of grass pollen immunotherapy. METHODS: We …