Inhibition of bacterial adherence by secretory immunoglobulin A: a mechanism of antigen disposal
RC Williams, RJ Gibbons - Science, 1972 - science.org
RC Williams, RJ Gibbons
Science, 1972•science.orgPreparations of secretory immunoglobulin A (S-IgA) isolated from human parotid fluid
specifically inhibited the adherence of Streptococcus strains to epithelial cells. Since
bacterial adherence is a prerequisite for colonization of mucous surfaces. S-IgA-mediated
inhibition of adherence would limit bacterial colonization. This mechanism can explain how
secretory immunoglobulins function in the disposal of bacterial antigens.
specifically inhibited the adherence of Streptococcus strains to epithelial cells. Since
bacterial adherence is a prerequisite for colonization of mucous surfaces. S-IgA-mediated
inhibition of adherence would limit bacterial colonization. This mechanism can explain how
secretory immunoglobulins function in the disposal of bacterial antigens.
Preparations of secretory immunoglobulin A (S-IgA) isolated from human parotid fluid specifically inhibited the adherence of Streptococcus strains to epithelial cells. Since bacterial adherence is a prerequisite for colonization of mucous surfaces. S-IgA-mediated inhibition of adherence would limit bacterial colonization. This mechanism can explain how secretory immunoglobulins function in the disposal of bacterial antigens.
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