Transcutaneous vagal nerve stimulation may elicit anti-and pro-nociceptive effects under experimentally-induced pain—a crossover placebo-controlled investigation
R Laqua, B Leutzow, M Wendt, T Usichenko - Autonomic Neuroscience, 2014 - Elsevier
Vagal nerve stimulation is a promising method for the treatment of pain. The aim was to
investigate the effect of non-invasive transcutaneous vagal nerve stimulation (TVNS) on the
experimental pain threshold (PT) and to compare it with placebo. PT of standardized
electrical stimulation was measured in 22 healthy male volunteers during two study
sessions. TVNS was applied to the auricular concha bilaterally for 35 min using 2 Hz/100 Hz
bursts with the intensity, which was individually maximal but non-painful. During the placebo …
investigate the effect of non-invasive transcutaneous vagal nerve stimulation (TVNS) on the
experimental pain threshold (PT) and to compare it with placebo. PT of standardized
electrical stimulation was measured in 22 healthy male volunteers during two study
sessions. TVNS was applied to the auricular concha bilaterally for 35 min using 2 Hz/100 Hz
bursts with the intensity, which was individually maximal but non-painful. During the placebo …