Endothelial and microcirculatory function and dysfunction in sepsis
JF Colbert, EP Schmidt - Clinics in chest medicine, 2016 - chestmed.theclinics.com
The microcirculation, comprised of less than 100 μm–diameter arterioles, capillary beds, and
draining venules, performs essential homeostatic functions, including oxygen delivery and
solute exchange. 1 Although this simple construct holds true across all human tissues, there
is substantial organ specificity of microcirculation structure, reflecting unique functions
assigned to different vascular beds. The kidney glomerulus, tasked with plasma
ultrafiltration, features afferent and efferent arterioles flanking a capillary network lined with …
draining venules, performs essential homeostatic functions, including oxygen delivery and
solute exchange. 1 Although this simple construct holds true across all human tissues, there
is substantial organ specificity of microcirculation structure, reflecting unique functions
assigned to different vascular beds. The kidney glomerulus, tasked with plasma
ultrafiltration, features afferent and efferent arterioles flanking a capillary network lined with …