[HTML][HTML] The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung
T Fujimori, AM Grabiec, M Kaur, TJ Bell, N Fujino… - Mucosal …, 2015 - Elsevier
Much of the biology surrounding macrophage functional specificity has arisen through
examining inflammation-induced polarizing signals, but this also occurs in homeostasis,
requiring tissue-specific environmental triggers that influence macrophage phenotype and
function. The TAM receptor family of receptor tyrosine kinases (Tyro3, Axl and MerTK)
mediates the non-inflammatory removal of apoptotic cells by phagocytes through the
bridging phosphatidylserine-binding molecules growth arrest-specific 6 (Gas6) or Protein S …
examining inflammation-induced polarizing signals, but this also occurs in homeostasis,
requiring tissue-specific environmental triggers that influence macrophage phenotype and
function. The TAM receptor family of receptor tyrosine kinases (Tyro3, Axl and MerTK)
mediates the non-inflammatory removal of apoptotic cells by phagocytes through the
bridging phosphatidylserine-binding molecules growth arrest-specific 6 (Gas6) or Protein S …