[HTML][HTML] Blood clots and TAM receptor signalling in COVID-19 pathogenesis
G Lemke, GJ Silverman - Nature reviews immunology, 2020 - nature.com
Nature reviews immunology, 2020•nature.com
We suggest that the exuberant blood clotting and immune hyper-reaction seen in patients
with COVID-19 may be exacerbated by depletion of the same regulator. This agent is protein
S, which is both an anticoagulant in the blood coagulation cascade and an activating ligand
for the immunosuppressive TAM family of receptor tyrosine kinases.
with COVID-19 may be exacerbated by depletion of the same regulator. This agent is protein
S, which is both an anticoagulant in the blood coagulation cascade and an activating ligand
for the immunosuppressive TAM family of receptor tyrosine kinases.
We suggest that the exuberant blood clotting and immune hyper-reaction seen in patients with COVID-19 may be exacerbated by depletion of the same regulator. This agent is protein S, which is both an anticoagulant in the blood coagulation cascade and an activating ligand for the immunosuppressive TAM family of receptor tyrosine kinases.
nature.com