[HTML][HTML] Escape from X inactivation in mice and humans
JB Berletch, F Yang, CM Disteche - Genome biology, 2010 - Springer
JB Berletch, F Yang, CM Disteche
Genome biology, 2010•SpringerA subset of X-linked genes escapes silencing by X inactivation and is expressed from both X
chromosomes in mammalian females. Species-specific differences in the identity of these
genes have recently been discovered, suggesting a role in the evolution of sex differences.
Chromatin analyses have aimed to discover how genes remain expressed within a
repressive environment.
chromosomes in mammalian females. Species-specific differences in the identity of these
genes have recently been discovered, suggesting a role in the evolution of sex differences.
Chromatin analyses have aimed to discover how genes remain expressed within a
repressive environment.
Abstract
A subset of X-linked genes escapes silencing by X inactivation and is expressed from both X chromosomes in mammalian females. Species-specific differences in the identity of these genes have recently been discovered, suggesting a role in the evolution of sex differences. Chromatin analyses have aimed to discover how genes remain expressed within a repressive environment.
Springer