Role of α-melanocyte stimulating hormone and melanocortin 4 receptor in brain inflammation

M Lasaga, L Debeljuk, D Durand, TN Scimonelli… - Peptides, 2008 - Elsevier
Inflammatory processes contribute widely to the development of neurodegenerative
diseases. The expression of many inflammatory mediators was found to be increased in
central nervous system (CNS) disorders suggesting that these molecules are major
contributors to neuronal damage. Melanocortins are neuropeptides that have been
implicated in a wide range of physiological processes. The melanocortin alpha-melanocyte
stimulating hormone (α-MSH) has pleiotropic functions and exerts potent anti-inflammatory …