Hypobetalipoproteinemia and abetalipoproteinemia
FK Welty - Current opinion in lipidology, 2014 - journals.lww.com
FK Welty
Current opinion in lipidology, 2014•journals.lww.comMutations causing low LDL-cholesterol and apoB have provided insight into lipid
metabolism, disease associations, and the basis for drug development to lower LDL-
cholesterol in disorders causing high levels of cholesterol. Early diagnosis and treatment are
necessary to prevent adverse sequelae from familial hypobetalipoproteinemia and
abetalipoproteinemia.
metabolism, disease associations, and the basis for drug development to lower LDL-
cholesterol in disorders causing high levels of cholesterol. Early diagnosis and treatment are
necessary to prevent adverse sequelae from familial hypobetalipoproteinemia and
abetalipoproteinemia.
Summary
Mutations causing low LDL-cholesterol and apoB have provided insight into lipid metabolism, disease associations, and the basis for drug development to lower LDL-cholesterol in disorders causing high levels of cholesterol. Early diagnosis and treatment are necessary to prevent adverse sequelae from familial hypobetalipoproteinemia and abetalipoproteinemia.
Lippincott Williams & Wilkins