Pressure overload creates right ventricular diastolic dysfunction in a mouse model: assessment by echocardiography

B Egemnazarov, A Schmidt, S Crnkovic… - Journal of the American …, 2015 - Elsevier
Background Noninvasive diagnostic tools for right ventricular (RV) dysfunction
measurements are increasingly being used, although their association with the pathologic
mechanisms of dysfunction is poorly understood. Although investigations have focused
mainly on RV systolic function, RV diastolic function remains mostly neglected. The aim of
this study was to test which echocardiographic parameters best reflect RV diastolic function
in mice. Methods Pulmonary artery banding (PAB) was used to induce RV pressure …