[PDF][PDF] Cross-presentation of tumor antigens is ruled by synaptic transfer of vesicles among dendritic cell subsets

S Balan, N Bhardwaj - Cancer Cell, 2020 - cell.com
S Balan, N Bhardwaj
Cancer Cell, 2020cell.com
Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node
resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al.
demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway
to load resident DCs for presentation to T cells.
Migratory dendritic cells (DCs) in tumors transport antigens and share them with lymph node resident DCs through cross-presentation. In this issue of Cancer Cell, Ruhland et al. demonstrate that transport and transfer of tumor antigens in vesicles is a dominant pathway to load resident DCs for presentation to T cells.
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