Association of urinary biomarkers of inflammation, injury, and fibrosis with renal function decline: the ACCORD trial
GN Nadkarni, V Rao, F Ismail-Beigi… - Clinical Journal of the …, 2016 - journals.lww.com
Results Baseline and 24-month levels of monocyte chemotactic protein-1-to-creatinine ratio
levels were higher for cases versus controls. The highest quartile of baseline monocyte
chemotactic protein-1-to-creatinine ratio had fivefold greater odds, and each log increment
had 2.27-fold higher odds for outcome (odds ratio, 5.27; 95% confidence interval, 2.19 to
12.71 and odds ratio, 2.27; 95% confidence interval, 1.44 to 3.58, respectively). IL-18-to-
creatinine ratio, kidney injury molecule-1-to-creatinine ratio, and YKL-40-to-creatinine ratio …
levels were higher for cases versus controls. The highest quartile of baseline monocyte
chemotactic protein-1-to-creatinine ratio had fivefold greater odds, and each log increment
had 2.27-fold higher odds for outcome (odds ratio, 5.27; 95% confidence interval, 2.19 to
12.71 and odds ratio, 2.27; 95% confidence interval, 1.44 to 3.58, respectively). IL-18-to-
creatinine ratio, kidney injury molecule-1-to-creatinine ratio, and YKL-40-to-creatinine ratio …