[HTML][HTML] Docosahexaenoic acid and the aging brain
The dietary essential PUFA docosahexaenoic acid [DHA; 22: 6 (n-3)] is a critical contributor
to cell structure and function in the nervous system, and deficits in DHA abundance are
associated with cognitive decline during aging and in neurodegenerative disease. Recent
studies underscore the importance of DHA-derived neuroprotectin D1 (NPD1) in the
homeostatic regulation of brain cell survival and repair involving neurotrophic, antiapoptotic
and antiinflammatory signaling. Emerging evidence suggests that NPD1 synthesis is …
to cell structure and function in the nervous system, and deficits in DHA abundance are
associated with cognitive decline during aging and in neurodegenerative disease. Recent
studies underscore the importance of DHA-derived neuroprotectin D1 (NPD1) in the
homeostatic regulation of brain cell survival and repair involving neurotrophic, antiapoptotic
and antiinflammatory signaling. Emerging evidence suggests that NPD1 synthesis is …